Maryland Small Ruminant Page - Anthelmintic Table

Drugs (Anthelmintics) Used to Control Internal Parasites in Sheep and Goats

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Not all drugs are approved for use in sheep and goats. The mention of non-approved products is for informational purposes only. They require extra label use and can only be used legally under the advice of a licensed veterinarian.
Trade Name	Drug Ingredient	Drug Family	Approved Species	Specificity	Labeled Dosage	Withdrawal Time
Cydectin® 0.5% pour-on for cattle	Moxidectin	ML	beef non-lactating dairy cattle	roundworms lungworms external parasites	5 ml/110 lbs. topical	cattle: 0 days slaughter
Dectomax® injectable 1%	Doramectin	ML	beef swine	roundworms lungworms external parasites	1 ml/110 lbs. (cattle) 1 ml/110 lbs (swine) Sub Q or IM	cattle: 35 days slaughter swine: 24 days slaughter
Dectomax® pour-on for cattle 0.5%	Doramectin	ML	cattle	roundworms lungworms external parasites	5 ml/110 lbs. topical	cattle: 45 days slaughter
Ivomec® Eprinex pour-on	Eprinomectin	ML	dairy cattle	roundworms lungworms external parasites	5 ml/110 lbs. topical	cattle: 0 days slaughter
Ivomec® pour-on for cattle	Ivermectin	ML	beef	roundworms lungworms external parasites	1 ml/22 lbs. topical	cattle: 48 days slaughter
Ivomec Plus Injection	Clorsulon Ivermectin	ML	beef	roundworms lungworms external parasites Adult liver flukes	1 ml/110 lbs. SQ	cattle: 49 days slaughter
Ivomec® injectable 1%	Ivermectin	ML	beef swine	roundworms lungworms external parasites	1 ml/110 lbs cattle. 1 ml/75 lbs. swine Sub-Q	cattle: 35 days slaughter swine: 18 days slaughter
Ivomec® sheep drench 0.08% Primectin™ Drench	Ivermectin	ML	sheep	roundworms lungworms external parasites	3 ml/26 lbs. oral	sheep: 11 days slaughter
Positive Pellet Goat Dewormer	Morantel Tartrate	TETR	goats	roundworms	1 lb./100 lbs as sole ration. may also mix with 1 or 2 parts feed, or top dress	0 days milk discard 30 days slaughter
Prohibit™ Drench Powder	Levamisole Hydrochloride	TETR	cattle sheep	roundworms intestinal worms lungworms	Depends on dilution	cattle: 2 days sheep: 3 days
Quest® 2% oral gel	Moxidectin	ML	horses	roundworms lungworms external parasites	0.4 mg/2.2 lbs.	n/a
Rumatel® Medicated Premix	Morantel Tartrate	TETR	cattle goats	roundworms	1/10 lb./100 lbs.	cattle: 14 days goats: 30 days
Safeguard® Panacur® liquid 10%	Fenbendazole	BZD	cattle, non-lactating goats	roundworms lungworms	2.3 ml/100 lbs. oral	cattle: 8 days slaughter 0 milk withdrawal goats: 6 days slaughter
Safeguard® Panacur® paste	Fenbendazole	BZD	cattle horses	roundworms lungworms	2.3 mg/lb. oral	cattle: 8 days slaughter
Strongid® T paste	Pytrantel Pamoate	TETR	horses	roundworms	2.27 mg/lb. oral	none
Synanthic® drench 9.06%	Oxfendazole	BZD	beef non-lactating dairy	roundworms lungworms tapeworms	2.5 ml/110 lbs. oral	cattle: 7 days slaughter
Tramiso/Levasole® drench	Levamisole	IMID	sheep cattle	roundworms intestinal worms lungworms	1 oz./100 lbs. 1 ml/50 lbs. oral	3 days slaughter
Tramisol/Levasole® injectable for cattle 13.65%	Levamisole	IMID	beef	roundworms lungworms	2 ml/100 lbs. Sub-Q	cattle: 7 days
Tramisol/Levasole® boluses/oblets	Levamisole	IMID	sheep	roundworms lungworms	1 bolus/50 lbs. oral	sheep: 3 days slaughter
Valbazen® drench 11.36%	Albendazole	BZD	cattle sheep	roundworms lungworms tapeworms adult liver fluke	3 ml/ 100 lbs. oral restricted during pregnancy	7 days slaughter (sheep)
Zimecterin® paste 1.87%	Ivermectin	ML	horses	roundworms lungworms external parasites	1 tube/1250 lbs. oral	n/a
Source: Product labels and FDA Approved Animal Drug Products Online Database System @ http://dil.vetmed.vt.edu/. Last Updated 10-Feb-2005 by Susan Schoenian. ©Copyright 2004. Maryland Small Ruminant Page.

Drug (chemical) families:

Benzimidazoles (BZD) - also called "white drenches"

Chemical name ends in "dazole."
Wide margin of safety with regards to dose.
No side effects.
Effective against tape worms, though fenbendazole is not officially labeled for tapeworms.
Widespread resistance reported; cross resistance among members.
Valbazen (Albendazole) should not be administered during the first 30 days of pregnancy and 30 days after removal of rams.

Levamisole products/Imidazothiazoles (IMID) or nicotinics- also called "clear drenches
Tetrahydropyrimidines

Narrow margin of safety - follow recommended dose carefully.
Effective against all worm stages, including hypobiotic larvae.
Resistance reported.
Cross resistance with tetrahydropyrimidines (TETR).

Macrocylic lactones - also called avermectins (ML)

Wide safety margin for all ages and stages in life.
Effective against all worm stages, including hypobiotic larvae.
The maximum safety dose is more than ten times the therapeutic dose.
ML's are safe to use on pregnant and lactating ewes, rams and ewes at breeding and all breeds and ages of sheep.
Moxidectin (Cydectin or Quest) is also registered to have a persistent effect against Haemonchus contortus and Ostertagia sp. This will provide protections and re-infection of these worms for a minimum of two weeks after drenching and may be a useful control feature.

A special note about oral dosing:

Oral dosing is usually the recommended route of administration for sheep and goats. Studies have shown oral dosing to be more effective than other routes of administration. Injectable products can be administered orally. Pour-on products should not be used on sheep and goats unless they are administered orally. Levamisole drench or oblets are preferred to Levamisole injectable due to a wider margin of safety.

A special note about goats:

Goats metabolize dewormers differently than sheep or cattle. The drugs clear their system faster. As a result, they require higher doses of the drugs for effective treatment, typically 1.5 to 2 times the cattle/sheep dose. Producers should consult with a veterinarian to determine the proper dosage for their animals and to discuss the use of drugs that are not labeled for sheep and/or goats.